Rachel Kline is a PhD student in Dr Tom Wishart’s lab working to identify overlaps between different types of MNDs (ie. childhood vs. adult onset) which may prove able to be targeted by drug treatments. She uses animal models of different MNDs to detect similar patterns between these distinct conditions, and then uses computer-generated predictive networks to hypothesise how these common factors might be contributing to the disease process. Finally, she is testing these identified factors for their ability to modify disease severity using the power of fruit fly genetics. Her project therefore aims to identify possible treatments whose use would not be limited to a single form of these devastating conditions.
Rachel has previously worked to investigate modifiers of the childhood-onset MND spinal muscular atrophy (SMA), first as an MScR student in Dr Lyndsay Murray’s lab (Euan MacDonald Centre), then as a research technician in Professor Chis Lorson’s lab (University of Missouri). Outside of science she is an avid runner and an adventurous cook!